United Kingdom-Manchester: Laboratory, optical and precision equipments (excl. glasses)

Type of document: Voluntary ex ante transparency notice
Country: United Kingdom
OJEU Ref: (2017/S 054-099531/EN)
Nature of contract: Supply contract
Procedure: Negotiated without a call for competition
Regulation of procurement: EU
Type of bid required: Not applicable

Voluntary ex ante transparency notice
Supplies
Directive 2014/24/EU

Directive 2014/24/EU

Section I: Contracting authority
I.1) Name and addresses
Official name: The University of Manchester
Postal address: Oxford Road
Town: Manchester
Postal code: M13 9PL
Country: United Kingdom
Contact Person: Central Procurement Office
Telephone: +44 01612752160
Email: procurement@manchester.ac.uk
Nuts code: UKD3
Internet address(es):
Main address:
Address of the buyer profile:

I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity
Education

Section II: Object
II.1) Scope of the procurement
II.1.1) Title: Automated, Real-time, Label-free, Biophysical Assay Platform.

Reference number: 2017/1253/ARLBP/SP
II.1.2) Main CPV code: 38000000
Supplementary CPV code: FG11
II.1.3) Type of contract Supplies
II.1.4) Short Description:
Automated, real-time, label-free, biophysical assay platform for mode of action compound profiling to support our ongoing small molecule drug discovery efforts a the Drug Discovery Unit at the CRUK Manchester Institute (CRUK MI).
II.1.6) Information about lots
The contract is divided into lots: no
II.1.7) Total value of the procurement(excluding VAT)
Lowest offer: 164000.00/ Highest offer: 165000.00 taken into consideration
Currency: GBP

II.2) Description
II.2.2)Additional CPV code(s)
Main CPV code: 38500000
Supplementary CPV code: FG11

II.2.3) Place of performance
Nuts code: UKD3 Main site or place of performance:CRUK Manchester Institute (CRUK MI), The University of Manchester.

II.2.4) Description of the procurement
The high-quality comprehensive characterization of molecular interactions including kinetics, affinity, specificity, comparability, concentration, and thermodynamics. Detailed kinetic and thermodynamic profiling of compound-target interactions (kon, koff, KD, ΔH and ΔS) in a medium-throughput fashion.

II.2.5) Award criteria
II.2.11) Information about options
Options: no
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds: no
Section IV: Procedure
IV.1) Description
IV.1.1) Type of procedure
Negotiated procedure without prior publication(in accordance with Article 32 of Directive 2014/24/EU)
IV.1.8) Information about the Government Procurement Agreement(GPA)
The procurement is covered by the Government Procurement Agreement: yes
IV.2) Administrative information

Section V: Award of contract/concession
Title: Automated, Real-time, Label-free, Biophysical assay platform

V.2) Award of contract/concession
V.2.1) Date of conclusion of the contract/concession award decision:2017-03-14
V.2.2) Information about tenders
The contract has been awarded to a group of economic operators: no
V.2.3) Name and address of the contractor
Official name: GE Healthcare Life Sciences
Postal address: Little Chalfont, Amersham Place
Town: Amersham
Postal code: HP7 9NA
Country: United Kingdom
Nuts code: UK
The contractor is an SME: no

V.2.4) Information on value of the contract/lot/concession(excluding VAT)
Lowest offer: 164000.00/ Highest offer: 165000.00 taken into consideration
Currency: GBP
for framework agreements – total maximum value for this lot
for contracts based on framework agreements, if required – value of contract(s) for this lot not included in
previous contract award notices

Section VI: Complementary informationVI.4) Procedures for review
VI.4.1) Review body
Official name: The University of Manchester
Town: Manchester
Country: United Kingdom
Internet address:

VI.4.4) Service from which information about the review procedure may be obtained
Official name: The University of Manchester
Postal address: Oxford Road
Town: Manchester
Postal code: M13 9PL
Country: United Kingdom
Internet address:

VI.5) Date of dispatch of this notice:
2017-03-15

Justification for the award of the contract without prior publication of a call for
competition in the Official Journal of the European Union
1.Justification for the choice of the negotiated procedure without prior publication of a call for competition in accordance with Article
32 of Directive 2014/24/EU
The works, supplies or services can be provided only by a particular economic operator for the following reason:
absence of competition for technical reasons

3.Explanation
Please explain in a clear and comprehensive manner why the award of the contract without prior publication in the Official Journal of the European Union
is lawful, by stating the relevant facts and, as appropriate, the conclusions of law in accordance with the directive:
In addition to the critical sensitivity advantages, the platform offers some unique features which are not available with other SPR platforms. These include the ability to perform single cycle kinetics (SCK) in addition to the more classical multi-cycle kinetics (MCK). The former technique offers a rapid screening method which can be used to obtain a full kinetic / affinity characterization of small molecules without the need for surface regeneration. Also uniquely, the platform can be used to derive transition state thermodynamics from kinetic rate constants whereby the potential of enthalpy and entropy correlations associated with chemical modifications in a lead series can be specified enabling a more robust and reliable drug discovery process. 1 key advantage of SPR over the other biophysical techniques is its enhanced sensitivity. The platform has no lower molecular weight limit for the detection of organic molecules and therefore can be employed for very low molecular weight compound screening e.g. fragments. It also offer the largest kinetic space in relation to association and dissociation rates with the baseline noise of this machine set at an industry leading < 0.03 RU. Also, the ability to work with organic solvents up to 12 % DMSO.