United Kingdom-Newcastle: (NU/1818) The Supply and Installation of a Multiplexed Platform for Measuring Protein Biomarkers with Spatial Resolution at Single Cell Scale

Type of document: Contract Notice
Country: United Kingdom
Publication Ref: (2022/S 000-028785/EN)
Nature of contract: Supply contract
Procedure: Open procedure
Type of bid required: Global bid

Contract notice
Supplies

Section I: Contracting authority
I.1) Name and addresses
Official name: Newcastle University
Postal address: Newcastle University, Procurement Services, Kingsgate
Town: Newcastle
Postal code: NE1 7RU
Country: United Kingdom
Contact Person: Dr Emma Barksby
Telephone: +44 1912086298
Email: emma.barksby@ncl.ac.uk
Internet address(es):
Main address:
Address of the buyer profile:

I.3) Communication
The procurement documents are available for unrestricted and full direct access, free of charge,at:
Additional information can be obtained from:
the above mentioned address
Tenders or requests to participate must be submitted:
electronically via:
I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity
Education

Section II: Object
II.1) Scope of the procurement
II.1.1) Title: (NU/1818) The Supply and Installation of a Multiplexed Platform for Measuring Protein Biomarkers with Spatial Resolution at Single Cell Scale

Reference number: DN637330
II.1.2) Main CPV code: 38000000
II.1.3) Type of contract: Supplies
II.1.4) Short Description: The Faculty of Medical Sciences (FMS) within Newcastle University conducts significant discovery and clinical research on human tissue (healthy and diseased) as well as tissues from other relevant biological models. As part of an MRC equipment award (potential), the University are seeking to purchase a technology that can measure multiple protein biomarkers on various tissues and cellular samples with single cell spatial resolution. Due to the sheer nature and complexity of the biological/clinical questions, the system must be able to detect a minimum of 150 protein biomarkers on the same tissue/cell sample. Such a platform will underpin existing work by the FMS core technology platforms including flow cytometry, Bio-imaging and single cell technologies.
As stated in the above background section, but to reiterate, this tender process is for an
analysis platform that is able to detect and measure over 100 protein biomarkers with single-cell level spatial and morphometric resolution in various tissue sections (fixed/frozen and formalin-fixed paraffin embedded – FFPE- samples) as well as immobilised suspension/adherent primary cells and cell lines. The system should be easy to use with set up and walk away features and be able to utilise a range of freely available reagents from various competitive suppliers. It should also be able to be operated in a high-throughput manner with options for multi-slide loading and automated staining/imaging as one unit. The system must also come with dedicated data analysis options to include single cell segmentation, phenotypic exploration and spatial mapping. The system will be operated and supported by the Newcastle Flow Cytometry and Single cell analysis core facility team as a collaboration with the Bio-Imaging Unit. As part of the offer, we are seeking on-site training for a minimum of three people in all aspects of the platform’s operation, including any associated data analysis packages. The offer must include the specified warranty, service and maintenance cover specified in Section 3.2. Please note that the University reserves the right not to make an award of contract. Notification from the MRC about the award of grant funding for the purchase of the platform will be confirmed at the beginning of November. To meet the MRC requirement for delivery, installation and payment the tender process will begin before funding is confirmed.
II.1.5) Estimated total value:
Value excluding VAT: 660000 Currency: GBP
II.1.6) Information about lots:
The contract is divided into lots: no
II.2) Description
II.2.2) Additional CPV code(s)
38000000

II.2.3) Place of performance
Nuts code:
II.2.4) Description of the procurement:
The Faculty of Medical Sciences (FMS) within Newcastle University conducts significant discovery and clinical research on human tissue (healthy and diseased) as well as tissues from other relevant biological models. As part of an MRC equipment award (potential), the University are seeking to purchase a technology that can measure multiple protein biomarkers on various tissues and cellular samples with single cell spatial resolution. Due to the sheer nature and complexity of the biological/clinical questions, the system must be able to detect a minimum of 150 protein biomarkers on the same tissue/cell sample. Such a platform will underpin existing work by the FMS core technology platforms including flow cytometry, Bio-imaging and single cell technologies.
As stated in the above background section, but to reiterate, this tender process is for an
analysis platform that is able to detect and measure over 100 protein biomarkers with single-cell level spatial and morphometric resolution in various tissue sections (fixed/frozen and formalin-fixed paraffin embedded – FFPE- samples) as well as immobilised suspension/adherent primary cells and cell lines. The system should be easy to use with set up and walk away features and be able to utilise a range of freely available reagents from various competitive suppliers. It should also be able to be operated in a high-throughput manner with options for multi-slide loading and automated staining/imaging as one unit. The system must also come with dedicated data analysis options to include single cell segmentation, phenotypic exploration and spatial mapping. The system will be operated and supported by the Newcastle Flow Cytometry and Single cell analysis core facility team as a collaboration with the Bio-Imaging Unit. As part of the offer, we are seeking on-site training for a minimum of three people in all aspects of the platform’s operation, including any associated data analysis packages. The offer must include the specified warranty, service and maintenance cover specified in Section 3.2. Please note that the University reserves the right not to make an award of contract. Notification from the MRC about the award of grant funding for the purchase of the platform will be confirmed at the beginning of November. To meet the MRC requirement for delivery, installation and payment the tender process will begin before funding is confirmed.
II.2.5) Award criteria

II.2.6) Estimated value:
Value excluding VAT: 660000 Currency: GBP
II.2.7) Duration of the contract,framework agreement or dynamic purchasing system
Duration in months: 96
This contract is subject to renewal: no
II.2.9) Information about the limits on the number of candidates to be invited
II.2.10) Information about variants
Variants will be accepted: no
II.2.11) Information about options
Options yes
Description of options: There are options for extended warranty, maintenance and servicing for up to 8 years.

II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:no
Section IV: Procedure
IV.1) Description
IV.1.1) Type of procedure:
Open procedureIV.1.8) Information about the Government Procurement Agreement(GPA)
The procurement is covered by the Government Procurement Agreement: yes
IV.2) Administrative information
IV.2.2) Time limit for receipt of tenders or requests to participate
Date: 2022-11-15 Local time: 12:00
IV.2.4) Languages in which tenders or requests to participate may be submitted:EN
IV.2.7) Conditions for opening tenders
Date: 2022-11-15 Local time: 14:00

Section VI: Complementary information
VI.1) Information about recurrence:
This is a recurrent procurement: no
VI.2) Information about electronic workflows
VI.4) Procedures for review
VI.4.1) Review body
Official name: Newcastle University
Town: Newcastle upon Tyne
Country: United Kingdom
Internet address:

VI.4.3) Review procedure
Precise information on deadline(s) for review procedures:
Newcastle University will incorporate a minimum 10 calendar day standstill period at the point information on the award of the contract is communicated to tenderers. This period allows unsuccessful tenderers to seek further debriefing before the contract is entered into. Applicants have 2 working days from notification of the award decision to request additional debriefing and 4 / 4 that information has to be provided a minimum of 3 working days before expiry of the standstill period. Such additional information should be requested from the address referred to in part 1.1 above. If an appeal regarding the award of a contract has not been successfully resolved, the Public Contracts Regulations 2015 provide for aggrieved parties who have been harmed or are at risk of harm by a breach of the rules to take action in the High Court (England, Wales and Northern Ireland). Any such action must be brought promptly. Where a contract has not been entered into the Court may order the setting aside of the award decision or order the authority to amend any document and may award damages. If the contract has been entered into the Court may only award damages

VI.5) Date of dispatch of this notice:2022-10-13